Derived From Nature, Driven By ScienceWhy DavosLife E3?Product RangeHealth BenefitsApplicationsQuality AssuranceDownloads

DERIVED FROM NATURE

Palm fruit is one of the richest natural sources of Tocotrienol-Rich Fraction, with a concentration of up to 800 mg/kg. DavosLife E3 is isolated from non-GMO palm fruits (Elaeis guineensis). DavosLife E3 is a naturally occurring Vitamin E which consists of full spectrum Tocotrienol isomers (α, β, γ and δ) and α-Tocopherol.

DRIVEN BY SCIENCE

Davos Life Science is dedicated to conduct and support research studies on the benefits of phytonutrients Our scientists have continually conducted research on the effects and mechanisms of Tocotrienol-Rich Fraction in the human body and consequently unlocked the potential of this natural phytonutrient. The on-going research activities also look into the benefits in applications for cosmetic and personal care products, as well as food and beverage products.

Research & Development

Davos Life Science has established R&D facilities in Singapore and Malaysia to spearhead cutting-edge research on phytonutrients into health benefits, dermatological applications and product innovations. Our researchers have successfully carried out major biological research activities pertaining to Tocotrienol-Rich Fraction through in-vivo, in-vitro and human clinical studies.

Our researchers have investigated the biological activities of DavosLife E3 Tocotrienol-Rich Fraction in three major therapy areas:

1. Metabolic Syndrome and Cardiovascular Health
2. Skin Care
3. Cellular Wellness and Protection

Our research studies on the health benefits of DavosLife E3 have been published in leading scientific publications including the European Journal of Nutrition, International Journal of Cancer, Pigment Cell & Melanoma Research, and Journal of Atherosclerosis and Thrombosis.

For its commitment in advancing research on Tocotrienol-Rich Fraction, Davos Life Science is a distinguished recipient of the “2010 Asia Pacific Excellence Award in Vitamin E Research” from Frost and Sullivan.

Explore our scientific publications
Learn more about Tocotrienols

WHY DAVOSLIFE E3?

DavosLife E3 contains a complete spectrum of Tocotrienol isomers (α, β, γ and δ) and α-Tocopherol at a ratio perfectly balanced by nature, working together synergistically for health and wellness.

Unique Source, Distinctive Values

Tocopherols and Tocotrienols are found naturally in various grains and seeds such as wheat, rice bran, soybean, palm fruit, grape seed, peanut, walnut and pecan. However, most of these grains and seeds contain only Tocopherols; only a few contain both forms. Tocotrienols are found mainly in palm fruit, wheat, and rice bran in the hard outer layer beneath the husk.

Rice bran, palm and annatto oils were described as some of the richest sources of Tocotrienols. However, none besides palm fruit oil contain all four Tocotrienol isomers. The palm fruit is the unique source of complete spectrum of Tocotrienols and α-Tocopherol. Extracts from rice bran oil have a Tocotrienols:Tocopherol ratio of 1:1 and annatto seeds contain predominantly 2 isomers, δ-Tocotrienol and γ-Tocotrienol.

Studies have shown that each Tocotrienol isomer has its own unique health benefits. For example, α-Tocotrienol has been shown to provide good neuroprotection while γ-Tocotrienol is beneficial for cardiovascular health and cellular protection. Therefore, the efficacy of DavosLife E3 could be amplified by the presence of the complete spectrum of Tocotrienols with α-Tocopherol.

Table: Typical Ratio of Tocotrienols and Tocopherols
Vitamin E Isomers Rice Bran1 Wheat Germ2 Soybean3 Corn3 Annatto DavosLife E3
α-Tocotrienol 25%  1%  ND  ND ND 26%
β-Tocotrienol ND  6%  ND  ND ND 3%
γ-Tocotrienol 19%  ND  ND  ND 10% 32%
δ-Tocotrienol 1%  ND  ND  ND 90% 8%
α-Tocopherol 45%  48%  7%  15% ND 24%
Others 10%  45%  93%  85% ND 7%
ND Not detected.
1 Tocotrienol-Rich Fraction concentrate from rice bran oil (Japanese origin).
2 Contains 26% β-Tocopherol.
3 Sheppard et al. (1993); corn may contain traces of Tocotrienols.

PRODUCT RANGE

Davos Life Science offers a wide range of DavosLife E3 products.

Tocotrienol-Rich Fraction Liquid

An amber colored oil containing the natural form of mixed Tocotrienols Tocopherol. It is miscible with oil, partially miscible with ethanol and immiscible with water. The product range includes:-

  • DavosLife E3 DVL 30
  • DavosLife E3 DVL 50
  • DavosLife E3 DVL 84
  • DavosLife E3 DVL 95
Tocotrienol-Rich Fraction Powder

An off-white/yellowish powder containing the natural form of mixed Tocotrienols Tocopherol. It is highly water-dispersible with minimum 30% total vitamin E blend, which is one of the highest in the market.

  • DavosLife E3 DVP 30-WD
Tocotrienol Isomers

Analytical kit with high purity up to 97% for each isomer

  • DavosLife E3 α-Tocotrienol, 100mg
  • DavosLife E3 β-Tocotrienol, 100mg
  • DavosLife E3 γ-Tocotrienol, 100mg
  • DavosLife E3 δ-Tocotrienol, 100mg
DavosLife E3 Bio-Enhanced 20

DavosLife E3 Bio-Enhanced 20 is a uniquely formulated product, offering 46% higher oral bioavailability than market product. It is a proprietary self-emulsifying delivery system (SEDS) formulation with Tocotrienol-Rich Fraction which makes it the preferred formulation for Brand Owners and manufacturers of dietary supplements.

  • DavosLife E3 Bio-Enhanced, 50 mg/softgel
  • DavosLife E3 Bio-Enhanced 20, bulk liquid
Learn More

HEALTH BENEFITS

Metabolic Syndrome and Cardiovascular Health
  • Improve lipid profile
  • Reduce homocysteine and protect against Ischemia
  • Promote liver health
  • Improve plasma glucose and insulin tolerance
Learn More
Neuroprotection and Cognitive Health
  • Reduce DNA damage in brain cells
  • Reduce the number of white matter lesions (WML)
  • Minimise stroke-related brain tissue damage
Learn More
Bone and Joint Health
  • Prevent the loss of bone cells
  • Reduce the risk of osteoporosis
Learn More
Skin Care
  • Anti-ageing with anti-inflammatory properties
  • Antioxidation
  • Skin lightening
  • Photoprotection
  • Prevent DNA damage and restore collagen production
  • Skin repair and rejuvenation
  • Skin hydration
Learn More
Cellular Wellness
  • Deliver excellent antioxidation in lipid systems
  • Anti-inflammatory effect via multiple pathways
  • Induce apoptosis in cancer cells
Learn More
Radiation Protection
  • Improve post irradiation survival
  • Reduces radiation induced oxidative stress
  • Accelerate the recovery after irradiation
Learn More

APPLICATIONS

Nutraceuticals

DavosLife E3 DVL range of products is available in high purity oil form for soft gels and liquid formulations. Our signature product, DavosLife E3 Bio-Enhanced 20, a patent pending SEDS formulated Tocotrienol-Rich Fraction, is clinically proven to deliver 46% higher oral bioavailability as compared to market product. DavosLife E3 DVP range of products is available in powder form for hassle-free incorporation into capsules, tablets and powdered formulations.

Cosmetic and Personal Care Products

DavosLife E3 DVL range of products is highly stable under wide range of pH conditions and temperature range, which make it ideal for formulation in cosmetic and personal care products.

Functional Foods and Beverages

As consumers are becoming increasingly aware of the value of functional food and beverage products, the need for scientifically proven and naturally derived ingredients to enhance the functions of food and beverage products is of primary importance. For this application, DavosLife E3 DVP 30-WD is highly recommended as it has better dispersion compared to market product.

We welcome you to contact our sales support team for further discussion.

QUALITY ASSURANCE

Product quality is our top priority.

Davos Life Science is a nutraceutical ingredient supplier, as such we are a Vital Link to the Brand Owners of supplements for its Brand Assurance. We have invested in the latest and advanced technologies to address global consumers’ concerns in support of our most important customers, the Brand Owners. Since March 2015, we have shared the success of our proprietary technology in meeting the following regulatory standards on Persistent Organic Pollutants (POPs) for DavosLife E3 range of products.

  • EU 1259/2011, Dioxins/Furans & Dioxin-like PCBs
  • EU 835/2011, Benzo(a) pyrene & PAHs
  • EP 7.0/2008:20813, Pesticides
  • EU 629/2008, Heavy Metals
  • Food Chemical Codex, Heavy Metals
  • USP 36 , Pesticides
  • Australia Therapeutic Goods Administration, Pesticides
  • China Food Safety National Standard for Maximum Levels of Contaminants in Foods, GB 2762-2012, Benzo(a) pyrene
  • Japan Food Sanitation Law and Food Safety
Generally Recognised As Safe (GRAS)

DavosLife E3 is GRAS affirmed by the U.S. Food and Drug Administration (FDA) in 2010 as a permitted ingredient to be formulated in dietary supplements, functional food and beverage products. It has also been approved for use in dietary supplements in Australia, Japan, Malaysia, Hong Kong, Singapore, Canada and the United States.

Safe As Used In Cosmetics

Safety assessment conducted by the Cosmetic Ingredient Review (CIR) Expert Panel concluded that Tocotrienol-Rich Fraction is safe as used in cosmetics.

DOWNLOADS

*DavosLife E3 was formerly known as Naturale3.

Journals