Tocotrienols:Emerging nutrients in cardiovascular and metabolic health
An increasing number of scientific researchers are recognising
and promoting Tocotrienols’ use to improve
cardiovascular and metabolic health conditions [5–9].
Fighting against cardiovascular disease
Cardiovascular disease (CVD) refers to the conditions that affect the heart or blood vessels. It is the leading cause of death and disability worldwide, with an estimated 17.3 million people died from this disease each year. A study predicted the global number of death caused by CVD to reach 23.6 million by 2030 . It is inevitably a major health problem lurking around us.
Efforts are made to tackle issues related to CVD. For instance, nutraceuticals such as vitamins and fish oil are directed towards promoting heart health and blood vessel health by reducing lipid (fat) levels, including cholesterol and triglyceride levels.
Promoting heart health with Tocotrienols
Low-density lipoprotein-cholesterol (LDL-C) and high triglyceride level can lead to the build-up of plaques in blood vessels which inhibits blood flow to the heart and other parts of our body. Plaque build-up can also cause inflammation which narrows the arteries and hinders the blood flow, increasing the risk of heart attack and stroke.
Tocotrienols help to lower LDL-C and triglyceride and delay the blockage formation in blood vessels. Tocotrienols can reduce up to 25% of LDL-C and triglyceride, reducing major CVD risk factors such as hyperlipidemia that may occur when there are too many lipids in the blood . In a Davos Life Sciences Pte Ltd’s study, Tocotrienols are proven effective in lowering the production and transport of triglycerides in subjects with elevated blood cholesterol levels, reducing triglyceride levels by as much as 28%. Tocotrienol-treated subjects showed decreasing average weight trends, body fat mass, body fat percentage and waist measurement over time.
Acting as a better alternative to statins
Tocotrienols can suppress the production of the enzyme essential for cholesterol production . Tocotrienols are valid alternatives to statins, the primary pharmacologic standard for treating lipid imbalance, as Tocotrienols are unlikely to cause side effects such as nerve dysfunction which can arise when statins are taken at higher doses. Being a natural compound with the United States Food and Drug Administration’s recognition as Generally Recognised As Safe (GRAS), Tocotrienols are undoubtedly the emerging functional nutrients for cardiovascular and metabolic health.
Promoting metabolic health with Tocotrienols
Tocotrienols are effective in promoting metabolic health and preventing metabolic syndrome with their potent anti-inflammatory activity.
Type 2 Diabetes
Type 2 diabetes is an emerging issue in most parts of the world. This is due to the increased availability and consumption of processed food and sugary drinks with high energy content but low nutritional value, combined with a sedentary and stressful lifestyle . As scientifically proven anti-diabetic agents, Tocotrienols can improve glucose tolerance and insulin sensitivity, two key parameters that are important to diabetes prevention [8, 12].
Obesity is a major risk factor for diabetes. Tocotrienols’ use as dietary supplements helps to deal with obesity by suppressing molecular pathways that encourage fat tissue formation [24, 25]. Besides, Tocotrienols can help lower low-grade inflammatory activity often associated with obesity [26, 27].
Metabolic syndrome may contribute to developing non-alcoholic fatty liver disease (NAFLD), a common medical condition that can eventually lead to inflammation and scarring of the liver. NAFLD can be reversed in the early stages. However, if it is left unchecked for too long, it may deteriorate and form liver cancer. A study showed that men and women with metabolic syndrome have 4 to 11 times higher risk of developing NAFLD than those without the condition .
Presently, there is no cure for late-stage NAFLD, also known as non-alcoholic steatohepatitis (NASH). Studies carried out by Davos Life Sciences showed that Tocotrienols could reduce triglyceride synthesis to improve NAFLD and protect the liver with their anti-inflammatory activity [12, 30].
About DavosLife E3 Complete
Tocotrienols are 100% natural, health-boosting ingredients that stimulate people from different parts of the world to take them as supplements for better cardiovascular and metabolic health. Tocotrienol supplements like DavosLife E3 Complete are scientifically formulated to supply you with adequate amount of Tocotrienols every day.
DavosLife E3 Complete formulation is patented in USA, Australia, New Zealand, Japan, Indonesia and India. It is clinically proven to have 46% higher bioavailability compared to a market sample, meaning it can be absorbed by human body more easily.
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